The Stamet’s Stack Microdosing Protocol
Microdosing Protocol
The Stamet’s Stack is a microdosing protocol developed by renowned mycologist Paul Stamets.
It combines three key components: psilocybin mushrooms, Lion’s Mane mushrooms, and niacin (vitamin B3).
This combination aims to enhance neurogenesis (the growth of new neurons), support brain health, and improve cognitive function.
Components and Their Roles:
1. Psilocybin Mushrooms:
At sub-perceptual doses, psilocybin is believed to promote neuroplasticity, potentially leading to improved mood, creativity, and cognitive flexibility.
2. Lion’s Mane Mushrooms:
This medicinal mushroom contains compounds that may stimulate nerve growth factor (NGF) production, supporting neuronal health and cognitive function.
3. Niacin (Vitamin B3):
Niacin acts as a vasodilator, expanding blood vessels and enhancing blood flow. This property is thought to aid in distributing the neurogenic compounds in psilocybin and Lion’s Mane more effectively throughout the nervous system.
Dosage and Schedule:
• Psilocybin:
A microdose typically ranges from 0.1 to 0.2 grams of dried psilocybin mushrooms.
• Lion’s Mane:
500 to 1,000 mg of high-quality Lion’s Mane extract powder.
• Niacin:
25 to 50 mg of niacin.
Protocol:
• Days 1–4:
Take the specified doses of psilocybin, Lion’s Mane, and niacin.
• Days 5–7:
No microdosing; this break helps prevent tolerance buildup.
• Cycle:
Continue this pattern for four weeks, followed by a two- to four-week break before potentially starting another cycle.
Potential Benefits:
• Neurogenesis and Neuroprotection:
The combination may promote the creation of new neurons and repair existing neurological damage.
• Cognitive Enhancement:
Users report improvements in memory, focus, and creativity.
• Emotional Well-being:
Some individuals experience reduced anxiety and improved mood.
Considerations:
• Niacin Flush:
Niacin can cause a harmless but sometimes uncomfortable flushing sensation, characterized by redness and tingling of the skin. I use “NO-FLUSH” NIACIN.
• Legal Status:
Psilocybin is a controlled substance in many regions. Ensure you are aware of and comply with local laws and regulations.
• Health Conditions:
Individuals with certain medical conditions or those taking specific medications should consult a healthcare professional before starting this protocol.
As with any supplement regimen, individual experiences may vary.
Ancestral Healing
Reverence for the Sacred Mushrooms
Sacred mushrooms, known in many cultures as “the flesh of the gods,” have long been revered as powerful allies for spiritual awakening, healing, and connection to the mysteries of existence. Across centuries and continents, from the ancient ceremonies of the Mazatec in Mexico to the shamanic traditions of Siberia, these fungi have been seen not merely as tools, but as sacred beings—teachers, guides, and bridges between the earthly and the divine.
To approach these mushrooms with reverence is to honor their role as ancient carriers of wisdom. They invite us to step beyond the confines of the ego and glimpse the vast interconnectedness of life, dissolving the barriers that separate us from our deeper selves, each other, and the Earth.
Reverence begins with preparation: creating a space of intention, respect, and quietude. It involves listening deeply to their teachings, which may emerge as visions, insights, or subtle shifts in awareness. The sacred mushrooms do not demand; they offer. They meet us where we are, revealing truths with a clarity that can be transformative when we approach them with humility and an open heart.
This relationship calls for reciprocity—a willingness to integrate their lessons into how we live, to honor the Earth from which they spring, and to carry forward the wisdom they impart. In this way, working with sacred mushrooms is not a transaction; it is a communion, a sacred dance between human and nature, spirit and soul.
To revere them is to recognize that their power is not in the substance alone but in the spirit they carry—an eternal reminder that the sacred is all around us, waiting for us to remember.